Previous reports have shown that bile acids bind to the G protein-coupled receptor TGR5 to potentiate thyroid hormone signaling in BAT, leading to increased energy expenditure and reduced body weight gain 38
Given its lipophilic properties and water insolubility, non-vesicular transport by specific carriers stands as the major mechanism of cholesterol transport between organelles
doi: 10.1172/jci.insight.120360 225 RodigSJGusenleitnerDJacksonDGGjiniEGiobbie-HurderAJinCet al
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